abstract：PURPOSE:To investigate serial changes in the bleb wall using anterior segment optical coherence tomography (AS-OCT) in patients who had undergone Ahmed glaucoma valve (AGV) implantation. METHODS:A total of 52 patients who had undergone AGV implantation were enrolled. Reflectivity and mean thickness of the bleb wall we...

journal_title：Acta ophthalmologica

authors： Jung KI,Park H,Jung Y,Park CK

更新日期：2015-06-01 00:00:00

abstract：PURPOSE:To determine alterations in the retina of patients with Alzheimer's disease (AD) by the newly developed technique of fluorescence lifetime imaging ophthalmoscopy (FLIO) in a pilot study. METHODS:FLIO set-up uses a scanning laser ophthalmoscope (HRA2, Heidelberg Engineering, Germany), which was modified by the ...

journal_title：Acta ophthalmologica

authors： Jentsch S,Schweitzer D,Schmidtke KU,Peters S,Dawczynski J,Bär KJ,Hammer M

更新日期：2015-06-01 00:00:00

abstract：PURPOSE:To compare various optic nerve head (ONH) parameters and peripapillary retinal nerve fibre layer (pRNFL) thickness between megalopapilla cases and normal control using spectral domain optical coherence tomography (SD-OCT) in children. METHODS:Fifty eyes with megalopapilla and 80 normal control eyes of totally ...

journal_title：Acta ophthalmologica

authors： Lee HS,Park SW,Heo H

更新日期：2015-06-01 00:00:00

abstract：PURPOSE:A recent threefold increase in laser treatment for advanced retinopathy of prematurity (ROP) triggered a nationwide preschool ophthalmic and developmental status among extremely preterm survivors. Here, we discuss refraction and visual acuity. METHODS:Survivors (n = 178) from a national birth cohort (February ...

journal_title：Acta ophthalmologica

authors： Fledelius HC,Bangsgaard R,Slidsborg C,laCour M

更新日期：2015-06-01 00:00:00

abstract：PURPOSE:Enzyme replacement therapy (ERT) was offered from year 2001 to patients with Fabry disease. The ophthalmic experience was analysed, as part of a general 10-year status. METHODS:A retrospective observational series comprising 39 patients (25 females, 14 males) closely followed by the endocrinologists, and with ...

journal_title：Acta ophthalmologica

authors： Fledelius HC,Sandfeld L,Rasmussen ÅK,Madsen CV,Feldt-Rasmussen U

更新日期：2015-05-01 00:00:00

abstract：:The main purpose of this thesis was to examine whether the Danish National Patient Registry (NPR) could be used to monitor and assess the quality of cataract surgery in Denmark by studying the risks of two serious postoperative complications following cataract surgery - retinal detachment (RD) and postoperative endoph...

journal_title：Acta ophthalmologica

authors： Bjerrum SS

更新日期：2015-03-01 00:00:00

abstract：PURPOSE:To identify the differences in posterior pole profiles between early normal tension glaucoma (NTG) patients with an initial central visual field (VF) loss and those with a peripheral VF loss. METHODS:Normal tension glaucoma patients with parafoveal scotoma (PFS; within a central 10° of fixation; superior, n=47...

journal_title：Acta ophthalmologica

authors： Choi JA,Park HY,Park CK

更新日期：2015-03-01 00:00:00

abstract：PURPOSE:To characterize frequency, morphological cause and time-dependent change of boundary line artefacts in optical coherence tomography (OCT) examinations of centre-involved diabetic macular oedema (ciDME) patients who underwent ranibizumab treatment with 1-year follow-up and to evaluate the impact of artefacts on ...

journal_title：Acta ophthalmologica

authors： Hodzic-Hadzibegovic D,Sander BA,Lund-Andersen H

更新日期：2015-02-01 00:00:00

abstract：PURPOSE:To evaluate the correlation between refractive astigmatism (RA) and anterior corneal astigmatism (ACA), and determine the internal astigmatism (IA) in 184 pseudophakic eyes. METHODS:The study was a prospective non-masked single-centre study. Patients were examined 8 weeks after phacoemulsification with implant...

journal_title：Acta ophthalmologica

authors： Bregnhøj JF,Mataji P,Naeser K

更新日期：2015-02-01 00:00:00

abstract：PURPOSE:Diabetic retinopathy is diagnosed by fundus photography and optical coherence tomography (OCT) scanning. However, adaptive optics (AO) imaging can be expected to add new aspects to the knowledge of diabetic retinopathy because photographic resolution is improved by reducing the influence of optical aberrations ...

journal_title：Acta ophthalmologica

authors： Bek T

更新日期：2014-12-01 00:00:00

abstract：PURPOSE:To evaluate the effect of photodynamic therapy (PDT) on central serous chorioretinopathy (CSC) compared with laser therapy and intravitreal injection of anti-vascular endothelial growth factor (anti-VEGF) drugs, and to find the maximum treatment effect with minimal dose and fluence of PDT. METHODS:A systematic...

journal_title：Acta ophthalmologica

authors： Ma J,Meng N,Xu X,Zhou F,Qu Y

更新日期：2014-12-01 00:00:00

abstract：PURPOSE:To investigate the intravitreal levels of potent vasoactive, angiogenic and extracellular matrix remodelling factors in the diabetic patients with simvastatin treatment. METHODS:This is an institutional, prospective, observational case-control study. Type-1 and type-2 diabetic patients on lipophilic simvastati...

journal_title：Acta ophthalmologica

authors： Tuuminen R,Sahanne S,Loukovaara S

更新日期：2014-11-01 00:00:00

abstract：PURPOSE:To investigate the amount of endothelial cell loss (ECL) and refractive predictability by femtosecond laser-assisted cataract surgery (FLACS) compared to conventional phacoemulsification cataract surgery (CPS). METHODS:Forty-seven patients had one eye operated by FLACS and the contralateral eye operated by CPS...

journal_title：Acta ophthalmologica

authors： Krarup T,Holm LM,la Cour M,Kjaerbo H

更新日期：2014-11-01 00:00:00

abstract：PURPOSE:Complex segregation analysis of 60 unrelated sporadic keratoconus (KC) families was performed to reveal the presumed mode of inheritance in our dataset. METHODS:Sixty probands, 212 family members and 212 age and gender matched healthy controls underwent clinical and videokeratographic examination. Family aggre...

journal_title：Acta ophthalmologica

authors： Kriszt A,Losonczy G,Berta A,Vereb G,Takács L

更新日期：2014-11-01 00:00:00

abstract：PURPOSE:To examine the public health impact of presbyopia regarding its effect on quality of life (QoL) and society in both the developed and developing worlds. METHODS:A database was created from articles found on PubMed, the Cochrane Library and Science Direct using the following search terms: presbyopia, QoL, accom...

journal_title：Acta ophthalmologica

authors： Goertz AD,Stewart WC,Burns WR,Stewart JA,Nelson LA

更新日期：2014-09-01 00:00:00

abstract：PURPOSE:To determine the effect of the axial length on the supernormal and false-positive sectors of the peripapillary retinal nerve fibre layer (RNFL) in healthy eyes using the normative database embedded in a spectral domain optical coherence tomographic (SD-OCT) instrument. METHODS:This was a prospective, observati...

journal_title：Acta ophthalmologica

authors： Yamashita T,Kii Y,Tanaka M,Yoshinaga W,Yamashita T,Nakao K,Sakamoto T

更新日期：2014-09-01 00:00:00

abstract：PURPOSE:To investigate the clinical efficacy and safety of an additional core vitrectomy to the standard therapy in patients with exudative age-related macular degeneration (ARMD). METHODS:In this prospective, controlled, single-centre study, 50 eyes of 50 patients (mean age: 74.1 ± 7.1; median 74 (69/78)) with ARMD w...

journal_title：Acta ophthalmologica

authors： Schramm K,Mueller M,Koch FH,Singh P,Kohnen T,Koss MJ

更新日期：2014-08-01 00:00:00

abstract：PURPOSE:Life expectancy is increasing. When corneal donors become older and corneal-grafted patients live longer with their graft, the need for good-quality donor tissue becomes more crucial. The aim of the present investigation is to study grafted recipients with a donor cornea with a total tissue age of more than 100...

journal_title：Acta ophthalmologica

authors： Visby E,Hjortdal J,Nielsen K

更新日期：2014-08-01 00:00:00

abstract：PURPOSE:  To determine the effect of pars plana vitrectomy (PPV) on oxygen saturation in retinal vessels. METHODS:  We performed a prospective consecutive interventional case series of 20 eyes of 20 patients with macular hole or epiretinal membrane. We performed automatic retinal oximetry (Oxymap Inc., Reykjavik, Icel...

journal_title：Acta ophthalmologica

authors： Sín M,Sínová I,Chrapek O,Prachařová Z,Karhanová M,Langová K,Rehák J

更新日期：2014-06-01 00:00:00

abstract：PURPOSE:  To evaluate the precision of techniques for measuring intraocular pressure (IOP) in corneas with presumably altered biomechanical properties. METHODS:  Intraocular pressure was measured with a Goldmann applanation tonometer (GAT), ocular response analyzer (ORA) and dynamic contour tonometer (DCT) in 70 eyes....

journal_title：Acta ophthalmologica

authors： Clemmensen K,Hjortdal J

更新日期：2014-06-01 00:00:00

abstract：PURPOSE:We present a genetic and clinical analysis of two sisters, 3 and 4 years of age, with nanophthalmos and macular folds. METHODS:Ophthalmological examination, general paediatric examination and molecular genetic analysis of the MFRP gene were performed in both affected siblings. RESULTS:Clinical analysis showed...

journal_title：Acta ophthalmologica

authors： Wasmann RA,Wassink-Ruiter JS,Sundin OH,Morales E,Verheij JB,Pott JW

更新日期：2014-05-01 00:00:00

abstract：PURPOSE:Our purpose was to evaluate the surgical outcome after intra-ocular lens exchange in patients who presented impairing visual complaints after primary multifocal intra-ocular lens (MIOL) implantation. In particular, the study was undertaken to look at the number of eyes that could be equipped with the bag-in-the...

journal_title：Acta ophthalmologica

authors： Tassignon MJ,Bartholomeeusen E,Rozema JJ,Jongenelen S,Mathysen DG

更新日期：2014-05-01 00:00:00

abstract：PURPOSE:A free autologous retinal pigment epithelium (RPE)-choroid graft can be harvested during transplantation surgery from a 6 or 12 o'clock site in the midperiphery. This study evaluated whether proliferative vitreoretinopathy (PVR) occurs more frequently in patients with an inferior donor site retinotomy, which is...

journal_title：Acta ophthalmologica

authors： van Zeeburg EJ,Maaijwee K,van Meurs JC

更新日期：2014-05-01 00:00:00

abstract：PURPOSE:To assess the prevalence of end-of-life visual impairment in patients followed for glaucoma. METHODS:Data of 122 patients followed for glaucoma who had died between July 2008 and July 2010 and who had visited the ophthalmology outpatient department of a large non-academic Dutch hospital were collected from the...

journal_title：Acta ophthalmologica

authors： Ernest PJ,Busch MJ,Webers CA,Beckers HJ,Hendrikse F,Prins MH,Schouten JS

更新日期：2013-12-01 00:00:00

abstract：PURPOSE:To evaluate the positivity rate of temporal artery biopsies (TAB) performed in suspects of giant cell arteritis (GCA) and to study the epidemiological and clinical factors associated to the biopsy result. METHODS:A retrospective, multicenter, case-control study was performed, including three hundred and thirty...

journal_title：Acta ophthalmologica

authors： González-López JJ,González-Moraleja J,Burdaspal-Moratilla A,Rebolleda G,Núñez-Gómez-Álvarez MT,Muñoz-Negrete FJ

更新日期：2013-12-01 00:00:00

abstract：PURPOSE:To establish whether differences in the assessment of diabetic macular oedema (DME) with either optical coherence tomography (OCT) or stereoscopic biomicroscopy lead to variability in the photocoagulation treatment of DME. METHODS:The differences in the assessment of DME with either OCT or stereoscopic biomicr...

journal_title：Acta ophthalmologica

authors： van Dijk HW,Verbraak FD,Kok PH,Oberstein SY,Schlingemann RO,Russell SR,Abràmoff MD

更新日期：2013-12-01 00:00:00

abstract：PURPOSE:  To describe sequential phacoemulsification-intraocular lens (IOL) implantation-posterior capsulorhexis-anterior vitrectomy in the management of phakic malignant glaucoma. METHODS:  Twenty consecutive patients (25 eyes) with phakic malignant glaucoma were enrolled at the Zhongshan Ophthalmic Center, Sun Yat-s...

journal_title：Acta ophthalmologica

authors： Liu X,Li M,Cheng B,Mao Z,Zhong Y,Wang D,Cao D,Yu F,Congdon NG

更新日期：2013-11-01 00:00:00

abstract：PURPOSE:To investigate whether introduction of item-response theory (IRT) analysis, in parallel to the 'traditional' statistical analysis methods available for performance evaluation of multiple T/F items as used in the European Board of Ophthalmology Diploma (EBOD) examination, has proved beneficial, and secondly, to ...

journal_title：Acta ophthalmologica

authors： Mathysen DG,Aclimandos W,Roelant E,Wouters K,Creuzot-Garcher C,Ringens PJ,Hawlina M,Tassignon MJ

更新日期：2013-11-01 00:00:00

abstract：PURPOSE:To evaluate and compare corneal biomechanical changes after deep anterior lamellar keratoplasty (DALK) versus penetrating keratoplasty (PK) using the ocular response analyzer (ORA). METHODS:This prospective comparative study included 65 eyes (65 patients). Patients were divided into three groups: DALK (20 eyes...

journal_title：Acta ophthalmologica

authors： Abdelkader A

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Primary open-angle glaucoma (POAG) is the main cause of irreversible blindness worldwide. Matrix metalloproteinases (MMPs) and their regulators (TIMPs and ILs) have been extensively studied as POAG risk factors. Recent reports have showed several single-nucleotide polymorphisms (SNPs) for MMPs, TIMPs and ILs...

journal_title：Acta ophthalmologica

authors： Markiewicz L,Majsterek I,Przybylowska K,Dziki L,Waszczyk M,Gacek M,Kaminska A,Szaflik J,Szaflik JP

更新日期：2013-11-01 00:00:00

abstract：PURPOSE:To investigate the presence and distribution of l-kynurenine aminotransferases immunoreactivity in human and animal lenses during cataract formation. METHODS:Immunohistochemistry was conducted using polyclonal antibodies against KAT I, KAT II and KAT III on sections of 26 anterior capsules from patients underg...

journal_title：Acta ophthalmologica

authors： Rejdak R,Oleszczuk A,Rummelt C,Turski WA,Choragiewicz T,Nowomiejska K,Ksiazek K,Thaler S,Zarnowski T,Okuno E,Grieb P,Zrenner E,Kruse F,Junemann AG

更新日期：2013-09-01 00:00:00

abstract：PURPOSE:Aquaporins (AQPs) are widely expressed and have diverse distribution patterns in the eye. AQPs 0-5 have been localized at the cellular level in human eyes. We investigated the presence of the more recently discovered AQPs 6-12 in the human eye. METHODS:RT-PCR was performed on fresh tissue from two human eyes d...

journal_title：Acta ophthalmologica

authors： Tran TL,Bek T,Holm L,la Cour M,Nielsen S,Prause JU,Rojek A,Hamann S,Heegaard S

更新日期：2013-09-01 00:00:00

abstract：PURPOSE:To evaluate effectiveness, tolerability and safety of repeated intravitreal injections of 0.5 mg ranibizumab for the treatment of neovascular age-related macular degeneration in routine medical practice in Germany. METHODS:A noninterventional study with 3470 patients treated in 274 medical centres according to...

journal_title：Acta ophthalmologica

authors： Finger RP,Wiedemann P,Blumhagen F,Pohl K,Holz FG

更新日期：2013-09-01 00:00:00

abstract：:This literature review is aimed at the evaluation of the potential for cataract prevention in Europe. It was performed using PubMed with Mesh and free-text terms. Studies included were (i) performed on a population of Caucasian origin at an age range of 40-95 years, (ii) cataract was clinically verified, (iii) drug re...

journal_title：Acta ophthalmologica

authors： Prokofyeva E,Wegener A,Zrenner E

更新日期：2013-08-01 00:00:00

abstract：PURPOSE:Study the clinical and microbiological characteristics and the prognostic factors of post-traumatic endophthalmitis. METHODS:Seventeen eyes were included between 2004 and 2010, with clinical and microbiological data collected prospectively. Conventional cultures and panbacterial PCR were performed on aqueous a...

journal_title：Acta ophthalmologica

authors： Cornut PL,Youssef el B,Bron A,Thuret G,Gain P,Burillon C,Romanet JP,Vandenesch F,Maurin M,Creuzot-Garcher C,Chiquet C,French Institutional Endophthalmitis Study (FRIENDS) Group.

更新日期：2013-08-01 00:00:00

abstract：PURPOSE:The Gloucestershire Diabetic Eye Screening Programme offers annual digital photographic screening for diabetic retinopathy to a countywide population of people with diabetes. This study was designed to investigate progression of diabetic retinopathy in this programme of the English NHS Diabetic Eye Screening Pr...

journal_title：Acta ophthalmologica

authors： Scanlon PH,Stratton IM,Histed M,Chave SJ,Aldington SJ

更新日期：2013-08-01 00:00:00

abstract：PURPOSE:Approximately 50% of patients with uveal melanomas develop metastases. Thus, it is important to improve our understanding of how melanoma metastases develop. METHODS:As part of a uveal melanoma micrometastasis study, we compared the detection rates of immunomagnetically selected (IMS) tumour cells in bone marr...

journal_title：Acta ophthalmologica

authors： Eide N,Hoifødt HK,Nesland JM,Faye RS,Qvale GA,Faber RT,Jebsen P,Kvalheim G,Fodstad Ø

更新日期：2013-06-01 00:00:00

abstract：PURPOSE:To study healing of retinal laser lesions in patients undergoing PRP using SD-OCT. METHODS:Moderate, light and barely visible retinal burns were produced in patients with proliferative diabetic retinopathy scheduled for PRP using 100-, 20- and 10-ms pulses of 532-nm laser, with retinal spot sizes of 100, 200 a...

journal_title：Acta ophthalmologica

authors： Lavinsky D,Cardillo JA,Mandel Y,Huie P,Melo LA,Farah ME,Belfort R,Palanker D

更新日期：2013-06-01 00:00:00

abstract：PURPOSE:To evaluate the diagnostic capacity of the Ocular Response Analyser's keratoconus match index (KMI) and keratoconus match probability (KMP) classification in a sample of keratoconus (KC) patients. METHODS:Keratoconus match index and KMP from 114 KC eyes, randomly selected from 114 patients with bilateral kerat...

journal_title：Acta ophthalmologica

authors： Labiris G,Gatzioufas Z,Sideroudi H,Giarmoukakis A,Kozobolis V,Seitz B

更新日期：2013-06-01 00:00:00

abstract：:Although the work for which Emil von Behring (1854-1917) was awarded the first Nobel Prize Winner for Medicine or Physiology in 1901 was on serum therapy, not only was he trained and worked as an ophthalmologist but he also wrote his doctoral dissertation on a practical ophthalmological topic whilst in Berlin under Ca...

journal_title：Acta ophthalmologica

authors： Grzybowski A,Wilhelm H

更新日期：2013-06-01 00:00:00